Abstract: For real-world big data applications, blockchain is used as a trusted infrastructure to build a patient-centric data sharing platform with data traceability and privacy protection functions. The data traceability function uses non-labeled data traceability based on Minhash and LSH Technology, combined with the blockchain, to achieve credible and verifiable data sources; privacy protection technology, a special privacy protection isolation area is designed, and a double-layer isolation protection mechanism for containers and virtual machines is adopted. The program downloads encrypted real-world data to this In the area, Analyze and process after decryption, and immediately destroy the decrypted plaintext after use. At the same time, use blockchain, control flow graph, minimum hash, local sensitive hash and other technologies to register the fingerprint of the analysis program, and verify the identity of the computing program.

Key words: Blockchain, Real-world data, Control Flow Graph, LSH, Minhash

摘要： 针对真实世界大数据应用，以区块链为基础设施，构建支持数据溯源、隐私保护、以患者为中心的数据共享平台，开发了原型系统进行了关键算法验证。数据的溯源功能，基于最小哈希的局部敏感哈希的非标注数据溯源技术，结合区块链，实现数据来源可追溯可信可验证；隐私保护功能，设计了专门的隐私保护隔离区，采用容器和虚拟机双层隔离保护机制，程序将加密发布的真实世界数据下载到隔离区内，解密后分析处理，用后解密明文立刻销毁,同时使用区块链、控制流图、最小哈希、局部敏感哈希等技术登记分析程序指纹，进行计算程序身份安全验证。

关键词: 区块链, 真实世界数据, 控制流图, 局部敏感哈希, 最小哈希